RAF Typhoon jets have operated alongside France's air force in a combined operation against an underground arms cache in Syria employed by the IS group, per a report from the British defence ministry.
The site, located using reconnaissance, was believed to be containing munitions and bombs, the announcement noted, and was situated in mountains just above the ancient city of Palmyra in the heart of Syria.
"The RAF jets employed Paveway IV guided bombs to strike a number of approach shafts providing entry to the site... initial indications indicate the target was engaged successfully," the ministry announced.
There was no sign of any civilian impact in the operation on Saturday evening and all the aircraft made a safe return, the defence officials confirmed.
The Typhoon FGR4s were supported by a Voyager aerial refuelling aircraft.
IS - also known as the so-called Islamic State - enforced militant control over large swathes of both Syria and Iraq before its territorial defeat in 2019.
"This strike underscores the UK's leading role, and resolve to operate in unison with our allies, to stamp out any revival of IS and their violent and radical beliefs in the area," the British Defence Secretary the minister stated.
British military aircraft have performed surveillance missions over Syria to "deter any attempted comeback" of IS following its defeat at the climactic battle in Baghuz in the year 2019, the authorities noted.
"I must thank every member of our armed forces involved in this operation for their skill and their valour," Healey said. "Including them were numerous British personnel deployed over the holidays. This action, to eliminate dangerous terrorists who endanger our safety, shows how our armed forces are ready to step up, all year round, keeping Britain secure at home and strong abroad."
Last December, the US military conducted what it termed a "major assault" targeting Islamic State objectives in the country, subsequent to an assault resulted in the deaths of two US troops and a civilian linguist in Palmyra.
The United Nations reports Islamic State still boasts between 5,000 and 7,000 fighters in Syria and Iraq.